Home

It 1-ms thus possible to foresee the dangers of keto-bemiclone if it were taken into account that it had been rut on the market extremaly recently. (...) ANSLINGER (United States of America) stated that the use of keto- bemidone was not prohibited by law in the Un:Ited States. (...) VAILLE (France) stated th'lt the manufacture and use of' keto-bemidom -were prohibitec; in r cil1:;e. He -wished ·so 1-,:::Dw whether the therapeutic value of' keto-bemido~o vlL.S eq1..

Case No. 2016-936 Keto (Applicant) v. Secretary-General of the United Nations (Respondent) ORDER No. 265 (2016) 1. (...) UNDT/2016/064, in the case of Keto v. Secretary-General of the United Nations, in which it dismissed Mr. Keto’s application as not receivable. 2. On 15 June 2016, Mr.

Both carbofuran-7-phenol and carbofuran can undergo oxidation to generate 3-hydroxy-carbofuran and 3-keto-carbofuran, which are conjugated and eliminated via urine. (...) It is noted that the assessment does not yet consider the revised residue definition for risk assessment (including free and conjugated residues of 3-keto carbofuran), and the establishment of appropriate conversion factors to take into account for residues of 3-keto carbofuran is still pending. (...) When triennial applications were simulated, 3-keto-carbofuran exceeded this trigger only in one case (FOCUS PEARL, Piacenza scenario) of the simulations.

Both carbofuran-7-phenol and carbofuran can undergo oxidation to generate 3-hydroxy-carbofuran and 3-keto-carbofuran, which are conjugated and eliminated via urine. (...) It is noted that the assessment does not yet consider the revised residue definition for risk assessment (including free and conjugated residues of 3-keto carbofuran), and the establishment of appropriate conversion factors to take into account for residues of 3-keto carbofuran is still pending. (...) When triennial applications were simulated, 3-keto-carbofuran exceeded this trigger only in one case (FOCUS PEARL, Piacenza scenario) of the simulations.

Both carbofuran-7-phenol and carbofuran can undergo oxidation to generate 3-hydroxy-carbofuran and 3-keto-carbofuran, which are conjugated and eliminated via urine. (...) It is noted that the assessment does not yet consider the revised residue definition for risk assessment (including free and conjugated residues of 3-keto carbofuran), and the establishment of appropriate conversion factors to take into account for residues of 3-keto carbofuran is still pending. (...) The PECgw for the metabolites 3-keto-carbofuran and 3-hydroxy-carbofuran exceeded the 0.1μg/L parametric drinking water limit only in a few cases of FOCUS simulations wh

She also notified the Secretary-General that WHO recommended placing the following substances in Schedule II of the 1971 Convention: N-benzylpiperazine (BZP), JWH-018, AM-2201, 3,4-methylenedioxypyrovalerone (MDPV) and methylone (beta-keto-MDMA) (see annex for the relevant extract of that notification). (...) The recommendations are that: (a) AH-7921 be placed in Schedule I of the 1961 Convention; (b) gamma-Butyrolactone (GBL), 1,4-butanediol, 25B-NBOMe (2C-B- NBOMe), 25C-NBOMe (2C-C-NBOMe) and 25I-NBOMe (2C-I-NBOMe) be placed in Schedule I of the 1971 Convention; (c) N-Benzylpiperazine (BZP); JWH-018; AM-2201; 3,4-methylenedioxypyrovalerone (MDPV); methylone (beta-keto-MDMA) and mephedronea be placed in Schedule II of the 1971 Convention. (...) Methylone Methylone (beta-keto-MDMA) is chemically (R,S)-1-(1,3-benzodioxol-5-yl)-2- (methylamino)propan-1-one.

ANSLINGER (United States) recalled the case of keto-bemidone, a drug whose suppression had been unanimously agreed upon by the authorities of the United States, where it had been invented, and by the manufacturer himself. The result had not been satisfactory, because a manufacturer in another country had se~n fit to make the drug and distribute it throughout the world. (...) The way in which the system worked had been shown in the case already quoted, in which the -manufactu:rer had agreed to suppress keto-bemidone. The chemical substances under consideration by the Expert Committee had been regarded as potential drugs; they had been tested on human beings and all been intended for general use as pharmaceutical preparations.

(j) Consideration of a proposal from the World Health Organization to place methylone (beta-keto-MDMA) in Schedule II of the 1971 Convention 27. (...) At the same meeting, the Commission decided by 49 votes to 1 to include methylone (beta-keto-MDMA) in Schedule II of the 1971 Convention. (...) Upon the adoption of the decisions on the scheduling of JWH-018, AM-2201, 3,4-methylenedioxypyrovalerone (MDPV), methylone (beta-keto-MDMA) and mephedrone, the representative of France noted that her Government would have preferred for those substances to be placed under Schedule I of the 1971 Convention.

Excellency t~le Gm·e:-nor in CG~.mc:!.l The President, Keto I:ruc:!:' i N .A. Gr:··.\ncil The Secretary, Trustceshi;?

.); 4-(3-hydroxyphenyl) -1-methyl-4-piperidyl ethyl ketone hydrochloride (known as Keto-bemidone); 1-methyl-4-metahydroxyphenyl-piperidine-4-carboxylic acid ethyl ester (known as Bemidone); -1, 3-dimethyl-4-phenyl-4-Propionoxy piperidine (known as NU-1196, or Nisentil); -1, 3-dimethyl-4-phenyl-4-Propionoxy piperidine (otherwise identified by symbol NU-1779). 4, 4-diphenyl-6-dimethylamino-heptanone-3 (also known as methadone, Amidone, Dolophine, Adanon, etc.); 4, 4-Diphenyl-5-methyl-6-dimethylamino-hexanone-3 (known as i some thodone); 6-dimethylamino-4, 4-diphenyl-3-heptanol (otherwise identified by symbol N.I.H.-2933); 6-dimethylamino-4, 4-diphoneyl-3-acetoxyheptane (otherwise identified by symbol N.I.H.-2953); 6-Horpholine-4, 4-diphenyl-3-heptanone (also known as CB-11.