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Primary eye and skin irritation tests of Eksmin in rabbits. JT-0082 1980. (...) QJT-0004 2006. An eye irritation study of Permethrin in rabbits. QJT-0005 2006. A skin irritation study of Permethrin in rabbits. QJT-0006 2006.
语言:英语
得分: 285.05 - https://www.fao.org/fileadmin/...ticides/Specs/Permetrhin08.pdf
数据资源: un
The fifth revised edition includes, inter alia, a new test method for oxidizing solids, new miscellaneous changes to further clarify the criteria for the hazard classes skin corrosion/irritation, severe eye damage/irritation and aerosols; revised and simplified classification and labelling summary tables; new codes for pictograms and revised and further rationalized precautionary statements.
语言:英语
得分: 284.85 - https://shop.un.org/zh/node/50275
数据资源: un
The fifth revised edition includes, inter alia, a new test method for oxidizing solids, new miscellaneous changes to further clarify the criteria for the hazard classes skin corrosion/irritation, severe eye damage/irritation and aerosols; revised and simplified classification and labelling summary tables; new codes for pictograms and revised and further rationalized precautionary statements.
语言:英语
得分: 284.85 - https://shop.un.org/zh/node/50271
数据资源: un
Studies that would provide information useful for the continued evaluation of the compound Further observations in humans Toxicological criteria for setting guidance values for dietary and non-dietary exposure to lindane Human exposure Relevant route, study type, species Results, remarks Short-term (1-7 days) Oral, toxicity, dog LD 50 = 40 mg/kg bw Dermal, toxicity, rabbit LD 50 = 900 mg/kg bw Inhalation, 4 h, toxicity, rat LC 50 = 1600 mg/m 3 Skin, irritation, rabbit Not irritating Eye, irritation, rabbit Slightly irritating Skin, sensitization, guinea-pig Not sensitizing Medium-term (1-26 weeks) Repeated inhalation, 90 days, toxicity, rat NOAEL = 0.6 mg/m 3 per day: clinical signs and increased cytochrome P450 enzymes Repeated dermal, 90 days, toxicity, rat/rabbit NOAEL = 10 mg/kg bw per day: hepatic effects Repeated oral, 90 days, toxicity, rat NOAEL = 0.75 mg/kg bw per day: changes in liver and kidney weight Repeated oral, developmental toxicity, rabbit No NOAEL for maternal toxicity NOAEL = 10 mg/kg bw per day: fetuses with 13 ribs Repeated oral, reproductive toxicity, rat NOAEL = 1 mg/kg bw per day: developmental toxicity and hepatic effects Long-term (one-year) Repeated oral, 2 years, toxicity/carcinogenicity, rat NOAEL = 0.5 mg/kg bw per day: hepatic changes and decreased survival; no carcinogenicity.
语言:英语
得分: 283.68 - https://www.fao.org/3/w8141e/w8141e0w.htm
数据资源: un
HEALTH HAZARDS : CLARIFICATION OF CHAPTER 3.2, SKIN CORROSION/IRRITATION / TRANSMITTED BY THE EXPERT FROM SWEDEN
GENERAL ST/SG/AC.10/C.4/2004/23 29 September 2004 Original: ENGLISH COMMITTEE OF EXPERTS ON THE TRANSPORT OF DANGEROUS GOODS AND ON THE GLOBALLY HARMONIZED SYSTEM OF CLASSIFICATION AND LABELLING OF CHEMICALS Sub-Committee of Experts on the Globally Harmonized System of Classification and Labelling of Chemicals Eighth session, 6-9 December 2004 Item 2(b) of the provisional agenda UPDATING OF THE GLOBALLY HARMONIZED SYSTEM OF CLASSIFICATION AND LABELLING OF CHEMICALS (GHS) Health hazards Clarification of Chapter 3.2, Skin Corrosion/Irritation Transmitted by the expert from Sweden 1. At the 7th Session of the Sub-Committee, the expert from Sweden introduced a paper (UN/SCEGHS/7/INF.11) suggesting that the Sub-Committee look further into the issue of classification of substances and mixtures which may not show an irritating or corrosive property in their dry state but may produce skin corrosion or irritation in contact with moist skin or mucous membranes. 2. (...) GE.04-23739 ST/SG/AC.10/C.4/2004/23 page 2 At the end of Section 3.2.2.2, add the following note: NOTE : Whereas liquid substances are tested neat, solid substances should be ground to fine powder and evaluated in the presence of water or an appropriate solvent in order to determine if irritation or corrosion may result when the solid substance is in contact with moist skin or mucous membranes. ___________________
语言:英语
得分: 282.8 - daccess-ods.un.org/acce...ST/SG/AC.10/C.4/2004/23&Lang=E
数据资源: ods
La présente cinquième édition révisée inclut notamment une nouvelle méthode d'épreuve pour les matières solides comburantes; divers amendements pour clarifier d'avantage les critères de classification pour les classes de danger de corrosion/irritation cutanée, lésions oculaires graves/irritation oculaire et aérosols; des tableaux récapitulatifs pour la classification et l'étiquetage révisés et simplifiés; de nouveaux codes pour les pictogrammes, et des conseils de prudence révisés et rationalisés d'avantage.
语言:英语
得分: 281.73 - https://shop.un.org/books/clas...produits-chimiques-sgh-5-43645
数据资源: un
The fifth revised edition includes, inter alia, a new test method for oxidizing solids, new miscellaneous changes to further clarify the criteria for the hazard classes skin corrosion/irritation, severe eye damage/irritation and aerosols; revised and simplified classification and labelling summary tables; new codes for pictograms and revised and further rationalized precautionary statements.
语言:英语
得分: 281.73 - https://shop.un.org/zh/node/43646
数据资源: un
La présente cinquième édition révisée inclut notamment une nouvelle méthode d'épreuve pour les matières solides comburantes; divers amendements pour clarifier d'avantage les critères de classification pour les classes de danger de corrosion/irritation cutanée, lésions oculaires graves/irritation oculaire et aérosols; des tableaux récapitulatifs pour la classification et l'étiquetage révisés et simplifiés; de nouveaux codes pour les pictogrammes, et des conseils de prudence révisés et rationalisés d'avantage.
语言:英语
得分: 281.73 - https://shop.un.org/ru/node/43645
数据资源: un
La présente cinquième édition révisée inclut notamment une nouvelle méthode d'épreuve pour les matières solides comburantes; divers amendements pour clarifier d'avantage les critères de classification pour les classes de danger de corrosion/irritation cutanée, lésions oculaires graves/irritation oculaire et aérosols; des tableaux récapitulatifs pour la classification et l'étiquetage révisés et simplifiés; de nouveaux codes pour les pictogrammes, et des conseils de prudence révisés et rationalisés d'avantage.
语言:英语
得分: 281.73 - https://shop.un.org/node/43645
数据资源: un
Toxicology profile of the dazomet technical material, based on acute toxicity, irritation and sensitization. Species Test Duration and conditions or guideline adopted Result (dazomet) Rat (m f) Oral 14 days, guideline not specified LD50 = 415 mg/kg bw Rat (m f) Dermal EPA/FIFRA; OECD, EEC LD50 > 2000 mg/kg bw Rat (m f) Inhalation EPA/FIFRA; OECD (403) LC50 = 8400 mg/m3 Rabbit (m f) Skin irritation EPA/FIFRA; OECD (404) Non-irritant Rabbit (m f) Eye irritation EPA/FIFRA; OECD; EC (8.3/467/EEC) Non-irritant Guinea pig ( f) Skin sensitization EPA/FIFRA; OECD (406) Non-sensitizing Dazomet is of moderate acute oral toxicity but of low dermal and inhalation toxicity. It was not irritating to skin and eyes and showed no skin-sensitizing properties. 16 of 21 DAZOMET EVALUATION 2001 Table 4. (...) The irritancy of methyl isothiocyanate is well known and it may have been responsible for the effects observed.
语言:英语
得分: 281.13 - https://www.fao.org/fileadmin/...s_Pesticides/Specs/dazomet.pdf
数据资源: un