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The hazard statement specified for category 2A in Chapter 3.3 is “Provoque une sévère irritation oculaire”. The hazard statement specified for Category 2B in Chapter 3.3 is “Provoque une irritation oculaire”. 3. (...) In Annex 3, Table A3.1.2 of the French version of the GHS, amend H319 as follows (added text underlined): “Provoque une sévère irritation des yeux oculaire”. 9. In Annex 3, Table A3.1.2 of the French version of the GHS, amend H320 as follows (added text underlined): “Provoque une irritation des yeux oculaire”. 10. (...) ST/SG/AC.10/C.4/2012/8 3 Annex Classe/ Catégorie Chapter 3.3 (English GHS) (p.140) Chapitre 3.3 (French GHS) (p. 154) Annexe I (p. 280) Annexe 3 Tableau A3.1.2 (p. 336) Annexe 3 Section 3 (p. 420 - 422) CLP Regulation Catégorie 1 Causes serious eye damage Provoque des lésions oculaires graves Provoque des lésions oculaires graves H318 : Provoque des lésions oculaires graves H318 : Provoque des lésions oculaires graves H318 : Provoque des lésions oculaires graves Catégorie 2A Causes serious eye irritation Provoque une sévère irritation oculaire Provoque une sévère irritation oculaire H319 : Provoque une sévère irritation des yeux H319 : Provoque des lésions oculaires graves H319 : Provoque une sévère irritation des yeux Catégorie 2B Causes eye irritation Provoque une irritation oculaire Provoque une irritation oculaire H320 : Provoque une irritation des yeux H320 : Provoque une irritation oculaire

Outcome (b) Conclusion on classification Classification as serious eye damage or eye irritant (appropriate category, as applicable) or no classification Outcome (a) No data or inconclusive b No data, skin irritant c , not classified for skin corrosion/irritation c or inconclusive b Conclusive Conclusive Conclusive No data, no extreme pH, extreme pH with data showing non-significant acid/alkaline reserve or inconclusive b No data, eye irritant, not classified for serious eye damage/eye irritation, skin irritant c , not classified for skin corrosion/irritation c or inconclusive b No data or inconclusive b No data or inconclusive b Conclusive Conclusive Tier 3 Classification based on conclusive human data, standard animal data or in vitro/ex vivo data for skin corrosion (see 3.3.2.5) Conclusive No data, skin irritant c , not classified for skin corrosion/irritation c or inconclusive b ”. (...) c It is recognized that not all skin irritants are eye irritants and that not all substances that are non-irritant to skin are non-irritant to the eye (see 3.3.2.5, 3.3.2.6, 3.3.2.8.4 and 3.3.2.9.1).” (...) ST/SG/AC.10/C.4/2021/4 16 3.3.5.1 Replace decision logic 3.3.1 with the following: “ Substance: Are there data/information to evaluate serious eye damage/eye irritation? Mixture: Does the mixture as a whole or its ingredients have data/information to evaluate serious eye damage/eye irritation?

The combined hazard statement: H315 + H320 “Causes skin and eye irritation” was introduced into Table A3.1.2 (see ST/SG/AC.10/C.4/2008/24) because many substances and mixtures have properties leading to classification with the following two hazard classes and categories: • Skin corrosion/irritation, category 2: “Causes skin irritation” (H315) • Serious eye damage/eye irritation, category 2B: “Causes eye irritation” (H320) 9. (...) The group concluded that it would be appropriate to retain H315 + H320 “Causes skin and eye irritation” for skin irritation, category 2 and eye irritation, category 2B, and introduce a new hazard combination statement of: H315 + H319 “Causes skin irritation and serious eye irritation” into Table A3.1.2 for skin irritation, category 2 and serious eye damage/eye irritation, category 2/2A. (...) Under column 2 “Health hazard statements (2)”, insert: “Causes skin irritation and serious eye irritation 1” Under column 3 “Hazard class (GHS chapter) (3)”, insert: “Skin corrosion/irritation (chapter 3.2) and serious eye damage/eye irritation (chapter 3.3)”.

Test materials in the irritation category are excluded from the mild irritation category.” (...) ST/SG/AC.10/40/Add.3 14 3.2.3.2.1 In the first sentence, replace “skin irritation/corrosion” with “skin corrosion/irritation potential”. 3.2.3.2.2 In the first sentence replace: • “lower corrosivity/irritancy classification” with “lower skin corrosivity/irritancy classification”; • “least corrosivity/irritant original” with “least skin corrosivity/irritant original”; • “affect the corrosivity/irritancy” with “affect the skin corrosivity/irritancy”. 3.2.3.2.3 In the first sentence replace “irritation/corrosion potential” and “toxicity” with “skin corrosion/irritation potential”. 3.2.3.2.4 In the first sentence, replace “for corrosion” with “for skin corrosion”. (...) The weight of evidence including information on skin irritation may lead to classification for eye irritation.

Chapter 3.3, Table 3.3.5, hazard statement for Category 2A 154 Annex 1, Table entitled « lésions oculaires graves/irritation oculaire », hazard statement for Category 2A 280 Provoque une sévère irritation oculaire des yeux. Annex 1, Table entitled « lésions oculaires graves/irritation oculaire », hazard statement for Category 2B 280 Chapter 3.3, Table 3.3.5, hazard statement for Category 2B 154 Annex 3, Section 3, A3.3.5.1, table for “lesions/oculaires graves/irritation oculaire”, hazard statement H320 422 Provoque une irritation oculaire des yeux. (...) Amend hazard statement H319 on page 421 (Annex 3, Section 3, A3.3.5.1, table for “lesions/oculaires graves/irritation oculaire”), to correct the error explained in paragraph 6, above, as follows: Provoque des lésions oculaires graves une sévère irritation des yeux. 12.

On the amendments to current H315+H320, several experts expressed their preference for the alternative proposal outlined in paragraph 17 of document ST/SG/AC.10/C.4/2021/1, i.e. to retain the existing combination statement H315+H320 for skin corrosion/irritation category 2 and serious eye damage/eye irritation 2B and to insert a separate new entry for H315+H319 for skin corrosion/irritation category 2 and serious eye damage/eye irritation category 2/2A. (...) French translation of the definition of “Eye irritation” in the GHS Informal document: INF.7 (Canada) 37. (...) In the last sentence, replace “irritation” with “skin irritation” and add “are also available” at the end of the paragraph.